Refine your search
Collections
Co-Authors
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Dikle, Ajit M.
- A Clinical Study of Cholelithiasis at a Tertiary Health Care Centre
Abstract Views :375 |
PDF Views:103
Authors
Affiliations
1 Professor and Head, Department of Surgery, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
2 PG Resident, Department of Surgery, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
1 Professor and Head, Department of Surgery, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
2 PG Resident, Department of Surgery, Dr. Vasantrao Pawar Medical College Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
Source
MVP Journal of Medical Sciences, Vol 6, No 2 (2019), Pagination: 109-113Abstract
Introduction: Cholelithiasis is the most common disease state involving the gallbladder and biliary tree. Gallstones become symptomatic only when they obstruct a visceral structure. In developing countries, there exists a trend toward an increasing prevalence of the risk factors for gallstone disease. Materials and Methods: Cases were selected after applying inclusion and exclusion criteria. Thereafter data collection was done by meticulous history taking, clinical examination, appropriate laboratory and radiological investigations, operative findings, and post operative evaluation of cases. Results: This study comprised of 52 cases. Female to male ratio was 15:11. The most common presenting complaint was pain in abdomen in 49 (94.23%) patients. On clinical examination most common sign was tenderness in 48 (92.31%) patients. Abdominal ultrasonography showed gallstones in all cases. Either laparoscopic or open cholecystectomy was performed. Complications included wound infection, haemorrhage, and bile duct injury. On histo-pathological examination the most common finding was chronic Cholecystitis seen in 39 (75.00%) cases. Conclusion: The incidence of disease was more in females. The most common complaint was pain and the most common sign was tenderness. Abdominal ultrasonography should be imaging study of choice for suspected cases of cholelithiasis. Laparoscopic cholecystectomy is the procedure of choice.Keywords
Cholecystectomy, Cholelithiasis.References
- Jackson PG, Evans SRT. Biliary system. In: Townsend Jr CM, Evers BM, Beauchamp RD, Mattox KL (Eds). Sabiston textbook of Surgery. 20th ed. Philadelphia: Elsevier Pub; 2017. p. 1482−519.
- Conlon K. The gall bladder and Bile ducts. In: Williams N.S., Bulstrode C.J.K., O’Connell P.R. (Eds). Bailey & Love’s Short Practice of Surgery. 26th ed. Boca Raton: CRC Press; 2013. P. 1097−117.
- Dutta U, Tandon R. Diseases of the Gall Bladder and Biliary Tract. In: Munjal Y, Sharma S, Agrawal A, Singal R, Gupta P, Sundar S et al (Eds). API Textbook of Medicine. 10th ed. Mumbai: The Association of Physicians of India; 2015. p. 1238−42.
- Sun H, Tang H, Jiang S, Zeng L, Chen E, Zhou T, Wang Y. Gender and metabolic differences of gallstone diseases, World Journal of Gastroenterology. 2009 Apr 21; 15(15):1886−91. https://doi.org/10.3748/wjg.15.1886. PMid: 19370788, PMCid: PMC2670418.
- Rachamalla RR, Markapuram KK, Satish S, Singh K. A one-year study of cholelithiasis at a tertiary care hospital of South India, Int. Surg. J. 2018; 5:2444−48. https://doi.org/10.18203/2349-2902.isj20182502.
- Tafazal H, Spreadborough P, Zakai D. Laparoscopic cholecystectomy: A prospective cohort study assessing the impact of grade of operating surgeon on operative time and 30day morbidity, Ann. R. Coll. Surg. Engl. 2018; 100(3):178−84 https://doi.org/10.1308/rcsann.2017.0171. PMid: 29484945, PMCid: PMC5930083.
- Naik JR, Surendar J. A clinical study of cholelithiasis. Paripex, Indian Journal of Research. 2017 Nov; 6(11). Cited on 2018 Nov 15. Available from: https://www.worldwidejournals.com/paripex/recent_issues_pdf/2017/November/November_2017_1509785939__23.pdf.
- Kodama H, Kono S, Todoroki I, Honjo S, et al. Gallstone disease risk in relation to body mass index and waisttohip ratio in Japanese men, Int. J. Obes. Relat. Metab. Disord. 1999 Feb; 23(2):211−16. https://doi.org/10.1038/sj.ijo.0800781. PMid: 10078858.
- Sharada B, Srinivas D. Clinical study of cholelithiasis, Int. J. Sci. Stud. 2017; 5(3):210−14. Available online at https://www.ijss-sn.com/uploads/2/0/1/5/20153321/ijss_jun_ oa42_-_2017.pdf.
- Ganey JB. Cholecystectomy: Clinical experience with a large series, Am. J. Surg. 1986; 352−57. https://doi.org/10.1016/0002-9610(86)90466-6.
- Sharma A. Towards a safer cholecystectomy-the fundus to porta approach, Indian J. Surg. 1997 Jun; 141−45.
- Srinivasa Rao K, Ravi K. A prospective study on cholelithiasis and its complications, Journal of Dental and Medical Sciences. Dec. 2017; 16(12):01−04.
- Attwood SE, Hill AD Hill, Mealy K, Stephens RB. A prospective comparison of laparoscopic versus open cholecystectomy, Annals of the Royal College of Surgeons of England. 1992; 74:397−400. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2497695/.
- Kum CK, Wong CW, Goh PM, Ti TK. Comparative study of pain level and analgesic requirement after laparoscopic and open cholecystectomy, Surg. Laparosc. Endosc. 1994 Apr; 4(2):139−41.
- Lujan JA, Parrilla P, Robles R, Marin P, Torralba JA, Garcia-Ayllon J. Laparoscopic cholecystectomy vs open cholecystectomy in the treatment of acute cholecystitis: A prospective study, Archives of Surgery. 1998; 133(2):173−75. https://doi.org/10.1001/archsurg.133.2.173. PMid: 9484730.
- Coccolini F, Catena F, Pisano M. Open versus laparoscopic cholecystectomy in acute cholecystitis, Systematic review and meta-analysis, Int. J. Surg. 2015 Jun; 18:196−204. https://doi.org/10.1016/j.ijsu.2015.04.083. PMid: 25958296.
- Awasthi N. A retrospective histopathological study of cholecystectomies, Int. J. Health Allied Sci. 2015; 4:203−06. https://doi.org/10.4103/2278-344X.160902.
- Catena F, Ansaloni L, Bianchi E, Di Saverio S, Coccolini F, et al. The ACTIVE (Acute Cholecystitis Trial Invasive Versus Endoscopic) Study: Multicenter randomized, doubleblind, controlled trial of laparoscopic versus open surgery for acute cholecystitis, Hepatogastroenterology J. 2013; 60(127):1552−56. Cited on 19 November 2018. Available from: https://www.ncbi.nlm.nih.gov/pubmed/24634923.
- A Study of Microbial Profile and Drug Resistance Pattern in the Patients with Diabetic Foot at a Tertiary Health Care Center
Abstract Views :228 |
PDF Views:92
Authors
Affiliations
1 Department of General Surgery, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
1 Department of General Surgery, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
Source
MVP Journal of Medical Sciences, Vol 7, No 1 (2020), Pagination: 9-15Abstract
Introduction: Diabetic Foot Ulcer (DFU) is a serious and common complication of Diabetes Mellitus (DM). India has been called “the diabetes capital of the world.” The most common cause of morbidity and mortality in DFU is infections. Diabetic foot wounds are commonly infected, and infection leads to the formation of microthrombi causing further ischemia, necrosis, and progressive gangrene. These types of situations necessitate limb amputation. Thus, accurate diagnosis of the causative organism is essential for the management of these cases. Aims and Objectives: To Study microbial profile as well as drug resistance pattern in the patients having diabetic foot at a tertiary care center. Methodology: Approval from institutional ethical committee was obtained. 62 patients of diabetic foot were selected for the present study over 1 year. Wound discharge culture and antibiotic sensitivity testing were carried out using standard microbiological procedures. Result: In the study carried out it was observed that the majority of the patients fell under the age group consisting of those >60. The most common organism was Staphylococcus followed by Streptococci, Enterococcus. Gram positive organisms were most commonly sensitive to Vancomycin. Gram negative organisms were susceptible to Piperacillin-Tazobactum. Maximum resistance was found to be for Gentamycin. Conclusion: From the study it can be conclusively noticed that majority patients belonged to the age group consisting of >60 Yrs. Gram positive organisms showed highest sensitivity to Vancomycin. In case of Gram negative organism’s antibiotic with highest sensitivity was Piperacillin-Tazobactam. Gentamicin was the drug with highest resistance. This resistance pattern to various pathogens in our study will be helpful in treatment of Diabetic foot in future.Keywords
Diabetic Foot, Diabetic Foot Ulcer (DFU), Drug Resistance PatternReferences
- Joshi SR, Parikh RM. India - diabetes capital of the world: now heading towards hypertension. Journal of the Association of Physicians of India. 2007; 55:323–4.
- Center for Disease Control and Prevention. National Diabetes Fact Sheet: National Estimates and General Information on Diabetes and Prediabetes in the United States, 2011. Atlanta, GA, USA: Department of Health and Human Services, Center for Disease Control and Prevention; 2011.
- Huang Y, Cao Y, Zou M, Luo X, Jiang Y, Xue Y, et al. A comparison of tissue versus swab culturing of infected diabetic foot wounds. International Journal of Endocrinology. 2016; 2016.
- https://doi.org/10.1155/2016/8198714. PMid:27123004 PMCid:PMC4829715.
- Wild S, Roglic G, Green A, Sicree R, King H. Global Prevalence of Diabetes. Diabetes Care. 2004 May; 27(5):1047–53. https://doi.org/10.2337/diacare.27.5.1047. PMid:15111519.
- Andersen CA, Roukis TS. The diabetic foot. Surgical Clinics of North America. 2007; 87:1149–77. https://doi.org/10.1016/j.suc.2007.08.001. PMid:17936480.
- Richard JL, Sotto A, Lavigne JP. New insights in diabetic foot infection. World Journal of Diabetes. 2011; 2:24–32. https://doi.org/10.4239/wjd.v2.i2.24. PMid:21537457 PMCid:PMC3083903.
- Ismail K, Winkley K, Stahl D, Chalder T, Edmonds M. A cohort study of people with diabetes and their first foot ulcer: The role of depression on mortality. Diabetes Care. 2007; 30:1473–9. https://doi.org/10.2337/dc06-2313. PMid:17363754.
- Bronze MS, Khardori R. Diabetic foot infections treatment and management. Medscape; 2016.
- Casqueiro J, Casqueiro J, Alves C. Infections in patients with diabetes mellitus: A review of pathogenesis. Indian Journal of Endocrinology and Metabolism. 2012; 16, Suppl S1:27–36. https://doi.org/10.4103/2230-8210.94253. PMid:22701840 PMCid:PMC3354930.
- Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk tests. Approved Standards, 9th ed. CLSI Document M2-A9, vol. 26, no. 1. Wayne, PA, USA.
- Jeffcoate WJ, Harding KG. Diabetic foot ulcers. Lancet. 2003; 361:1545–51. https://doi.org/10.1016/S01406736(03)13169-8.
- Lipsky BA. A report from the international consensus on diagnosing and treating the infected diabetic foot. Diabetes/ Metabolism Research and Reviews. 2004; 20(Suppl. 1):S68– 77. https://doi.org/10.1002/dmrr.453. PMid:15150818.
- Frykberg RG. An evidence-based approach to diabetic foot infections. American Journal of Surgery. 2003; 186:44S– 54S. https://doi.org/10.1016/j.amjsurg.2003.10.008. PMid:14684226.
- Lipsky BA, Berendt AR, Deery HG, Embil JM, Joseph WS, Karchmer AW, et al. Diagnosis and treatment of diabetic foot infections. Clinical Infectious Diseases. 2004; 39:885– 910. https://doi.org/10.1086/424846. PMid:15472838.
- Benwana KA, Mulla AA, Rotimi VO. A study of the microbiology of diabetic foot infections in a teaching hospital in Kuwait. Journal of Infection and Public Health. 2012; 5:1–8 . https://doi.org/10.1016/j.jiph.2011.07.004. PMid:22341838.
- Jain SK, Barman R. Bacteriological profile of diabetic foot ulcer with special reference to drug-resistant strains in a tertiary care center in North-East India. Indian Journal of Endocrinology and Metabolism. 2017; 21:688–94. https:// doi.org/10.4103/ijem.IJEM_546_16. PMid:28989875 PMCid:PMC5628537
- Khan DM, Moosabba MS. Prevalence of diabetic foot ulcer infections associated with Gram negative bacteria with special reference to drug resistant isolates. International Journal of Biomedical Research. 2016; 7(11):765–70.
- Saseedharana S, Sahu M, Chaddh R. Epidemiology of diabetic foot infections in a reference tertiary hospital in India. Brazilian Journal of MicrobioIology. 2018; 49:401–6.
- https://doi.org/10.1016/j.bjm.2017.09.003. PMid:29157899 PMCid:PMC5914140.